The impact of the variant on RNA or protein purpose, dependant on experimental evidence from submitters.
This benefit is calculated by NCBI determined by info from submitters. Read through our principles for calculating the review position. The quantity of submissions which add to this assessment position is proven in parentheses.
There is no useful evidence in ClinVar for this variation. When you've got produced purposeful knowledge for this variation, make sure you take into consideration distributing that details to ClinVar.
The global minimal allele frequency calculated through the a thousand Genomes Venture. The minimal allele at this place is indicated in parentheses and should be different through the allele represented by this VCV history.
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Read through our guidelines for calculating the review status. This column also includes a backlink to your submitter’s assertion conditions if offered, and the collection technique.
The volume of variants in ClinVar which can be contained inside this gene, which has a connection to perspective the listing of variants.
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Stars symbolize the aggregate critique status, or the extent of overview supporting the aggregate germline classification for this VCV record.
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